ZCL278

Active small molecule, Products,

Cat No:LP000254 Product Name:ZCL278 CAS No:587841-73-4 Purity: ≥99% Solubility: In DMSO Storage: -10°C ZCL278 as a potent, cell-permeable Cdc42-specific inhibitor that suppresses actin-based cellular functions, including Golgi organization and cell motility.In Swiss 3T3 fibroblast cultures, ZCL278 abolishes microspike formation and disrupted GM130-docked Golgi structures, two of the most prominent Cdc42-mediated subcellular events. ZCL278 reduces the […]

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Crenolanib(CP-868596)

Active small molecule, Products, , ,

Cat No:LP000253 Product Name:CP868596 CAS No:670220-88-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C Crenolanib has 25-fold more affinity for PDGFRA/B compared with KIT, and is approximately 135-fold more potent than imatinib for inhibiting the PDGFRA D842V mutation. The IC50 for crenolanib for a KIT exon 11 deletion mutant kinase is greater than 1,000 versus 8 […]

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