PD 153035 HCl(AG-1517)

Active small molecule, Products, ,

Cat No:LP000258 Product Name:PD153035 HCl CAS No:153436-54-5 Purity: ≥99% Solubility: In DMSO Storage: -10°C Overactivity of the epidermal growth factor receptor-associated tyrosine kinase (EGFR) has been associated with cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread.1 PD 153035 is a highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM; […]

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PD 169316

Active small molecule, Products,

Cat No:LP000257 Product Name:PD169316 CAS No:152121-53-4 Purity: ≥99% Solubility: In DMSO Storage: -10°C p38 is a member of the mitogen-activated protein kinase (MAPK) superfamily of enzymes that play an important role in signal transduction. PD 169316 is a selective inhibitor of p38 MAPK.1 It inhibits p38 MAPK with an IC50 of 89 nM, whereas the […]

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