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CO-1686

Feb 25, 2018adminActive small molecule, Products1374640-70-6, CO1686

Cat No:LP000266 Product Name:CO1686 CAS No:1374640-70-6 Purity: ≥99% Solubility: In DMSO Storage: -10°C CO-1686 (0.1 μM) inhibits EGFR potently and irreversibly, and inhibits more than 50% of 23 targets. CO-1686 potently and selectively inhibits growth of NSCLC cells expressing mutant EGFR and induces apoptosis. CO-1686 resistant NSCLC cell lines are sensitive to AKT inhibition.

Ki8751

Feb 25, 2018adminActive small molecule, Products228559-41-9, KI8751

Cat No:LP000265 Product Name:Ki8751 CAS No:228559-41-9 Purity: ≥99% Solubility: In DMSO Storage: -10°C Ki8751 inhibits VEGFR-2 phosphorylation at an IC50 value of 0.90 nM, and also inhibits the PDGFR family members such as PDGFRR and c-Kit at 67 nM and 40 nM, respectively. However, Ki8751 does not have any inhibitory activity against other kinases such […]