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TAK-632

Feb 25, 2018adminActive small molecule, Products1228591-30-7, TAK632

Cat No:LP000278 Product Name:TAK632 CAS No:1228591-30-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C TAK-632 is a slow off-rate inhibitor of Raf kinases (IC50s = 8.3, 2.4, and 1.4 nM for wild type B-Raf, mutant B-RafV600E, and c-Raf, respectively).1 It demonstrates 14-1,200-fold selectivity for Raf over a panel of 26 different kinases.1 TAK-632 shows significant antiproliferative […]

SB1317(TG02)

Feb 25, 2018adminActive small molecule, Products937270-47-8, SB1317

Cat No:LP000277 Product Name:SB1317 CAS No:937270-47-8 Purity: ≥99% Solubility: In DMSO Storage: -10°C SB1317 has a highly novel kinase inhibitory spectrum inhibiting 17 kinases from a panel of 63, 11 of which are CDK/JAK/FLT family members. The others, Lck, Fyn, Fms, TYRO3, ERK5, and p38δ, are implicated in inflammatory and proliferative processes. Human CYP1A2, 3A4, […]