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GSK343

Feb 25, 2018adminActive small molecule, Products1346704-33-3, GSK343

Cat No:LP000280 Product Name:GSK343 CAS No:1346704-33-3 Purity: ≥99% Solubility: In DMSO Storage: -10°C The histone H3 lysine 27 (H3K27) methyltransferase EZH2 plays an important role in regulating gene expression, and its aberrant activity is linked to the onset and progression of cancer.1 GSK343 is a cell-permeable EZH2 inhibitor (IC50 = 4 nM) that is 60-fold […]

Valdecoxib,Bextra

Feb 25, 2018adminActive small molecule, Products81695-72-7, Valdecoxib

Cat No:LP000279 Product Name:Valdecoxib CAS No:81695-72-7 Purity: ≥99% Solubility: In DMSO Storage: -10°C Valdecoxib is a non-steroidal anti-inflammatory drug that selectively inhibits COX-2, exhibiting IC50 values of 26.1 and 0.87 µM for COX-1 and COX-2, respectively, in a human whole blood assay.1 The COX-2 selectivity ratio of 30 for valdecoxib in this assay is similar […]