LookPharma – Page 598 – Look Pharma Limited

Ganetespib(STA-9090）

Cat No:LP000286 Product Name:STA-9090,Ganetespib CAS No:888216-25-9 Purity:≥99% Solubility:In DMSO Storage:-10°C Ganetespib is a resorcinol-based second generation inhibitor of heat shock protein 90 (Hsp90) that demonstrates an IC50 value of 4 nM in cells.1 It induces growth inhibition and apoptosis of both hematologic and solid tumor cells (EC50 values range from 2 to 20 nM).1,2 Ganetespib […]

Lenvatinib(E-7080)

Feb 25, 2018adminActive small molecule, Products417716-92-8, E7080

Cat No:LP000285 Product Name:Lenvatinib,E-7080,ER-203492-00 CAS No:417716-92-8 Purity:≥99% Solubility:In DMSO Storage:-10°C Lenvatinib is a potent inhibitor of VEGF-R2 and VEGF-R3 kinase activities with IC50 values of 4.0 and 5.2 nM, respectively.1,2. It is slightly less potent against the related receptor kinases VEGF-R1, FGF-R1, PGDFR3β and Kit (IC50 values of 22, 46, 39, and 100 nM, respectively). […]