Cat No:LP000290 Product Name:P529,Palomid 529 Synonyms:P529;RES-529;SG 00529 CAS No:914913-88-5 Purity:≥99% Solubility:In DMSO Storage:-10°C Palomid 529 (P529) is an inhibitor of mammalian target of rapamycin complex (mTORC) formation.1 It is a derivative of a non-steroidal estrogen antagonist that has anti-angiogenic and anticancer activity but lacks estrogen receptor binding activity in estrogen binding assays in vitro. Palomid […]
Cat No:LP000289 Product Name:OSU-03012 CAS No:742112-33-0 Solubility:In DMSO Storage:-10°C Description: PDPK1 (PDK1) inhibitor; inhibits Akt signaling Chemical Name: 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide Purity: ≥98% (HPLC) PDPK1 (PDK1) inhibitor; inhibits Akt signaling. Induces apoptosis of PC-3 and medulloblastoma cells, and inhibits growth of a number of tumor cell lines. Sensitizes radiotherapy-induced cell death and enhances cytotoxic effects of chemotherapeutic […]