AVL-292

Active small molecule, Products,

Cat No:LP000292 Product Name:AVL-292 Synonyms:CC-292,Spebrutinib CAS No:1202757-89-8 Purity:≥98% Solubility:In DMSO Storage:at -20°C 2 years Bruton’s tyrosine kinase (BTK) is a non-receptor tyrosine kinase involved in signal transduction pathways regulating the proliferation, activation, and differentiation of B cells. AVL-292 is an orally available, selective, and irreversible inhibitor of BTK (IC50 = 0.5 nM in vitro in […]

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SB1518(Pacritinib)

Active small molecule, Products, ,

Cat No:LP000291 Product Name:SB1518,Pacritinib CAS No:937272-79-2 Purity:≥98% Solubility:In DMSO Storage:at -20°C 2 years FMS-like tyrosine kinase 3 (FLT3) and Janus kinase 2 (JAK2) are tyrosine kinases that mediate cytokine signaling and are frequently mutated in cancers, particularly acute myeloid leukemia.1,2 Pacritinib is an inhibitor of both FLT3 and JAK2 (IC50s = 22 and 23 nM, […]

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