CP673451

Active small molecule, Products,

Cat No:LP000300 Product Name:CP673451 CAS No:343787-29-1 Purity:≥98% Formula:C24H27N5O2 Storage:At-20°C 3 years Powder Molecular Weight:417.50 Solubility:In DMSO,28 mg/mL heating (67.06 mM) Synonyms:1-[2-[5-(2-Methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-ylamine In Vitro: CP-673451 efficiently suppresses the PDGFR downstream signaling pathway. It inhibits phosphorylation of Akt, GSK-3β, p70S6, and S6 in A549 cells in a concentration-dependent manner. CP-673451 (0.0625-4 μM) significantly reduces the viability of […]

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SC-396658(AdipoRon)

Active small molecule, Products, ,

Cat No:LP000299 Product Name:SC-396658,AdipoRon CAS No:924416-43-3 Purity:≥99% Solubility:In DMSO Storage:At -20°C 2 years Adiponectin expressed by adipocytes exerts antidiabetic effects by binding to adiponectin receptor (AdipoR)1, which activates AMPK pathways, and AdipoR2, which activates PPARα pathways. AdipoRon is an orally active small molecule AdipoR agonist that binds AdipoR1 and AdipoR2 with KD values of 1.8 and […]

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