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PIK-294

Cat No:LP000308 Product Name:PIK-294 CAS#900185-02-6 Molecular Formula: C28H23N7O2 Molecular Weight: 489.53 Analysis of the specific Class I PI3 Kinase catalytic isoforms p110α (IC50=10 μM), p110β (IC50=0.49 μM), p110δ (IC50=0.01 μM) and p110γ (IC50=0.16 μM) using the inhibitor PIK-294 indicates differential roles in CXCL8-induced neutrophil migration. PIK-294 inhibits both chemokinetic and chemotactic CXCL8-induced migration[1]. When cells […]

Ibutamoren Mesylate(MK-677）

Jun 15, 2018adminActive small molecule, Products159752-10-0, Ibutamoren Mesylate, MK-0677, MK-677

Cat No:LP000307 Product Name:Ibutamoren Mesylate;MK-677; MK-0677 CAS#159752-10-0 Molecular Formula:C27H36N4O5S.CH4O3S Molecular Weight:624.77 Ibutamoren mesylate (5 mg/kg/day) results in a statistically significant increases body weight gain and increases serum IGF-1 and GH levels in dogs. Ibutamoren mesylate results in no significant increase in CSF IGF-1 or GH levels on days 7 or 15 of the study[1]. Pretreating […]