Cat No:LP000314 Product Name:JH-II-127 CAS#1700693-08-8 Molecular Formula：C19H21ClN6O3 Molecular Weight：416.86 JH-II-127 is a potent and selective inhibitor of both wild-type and G2019S mutant LRRK2. JH-II-127 substantially inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2 and G2019S mutant at a concentration of 0.1-0.3 μM in a variety of cell types and is capable of inhibiting Ser935 […]
Cat No:LP000313 Product Name:U-104;NSC 213841 CAS#178606-66-1 Molecular Formula:C13H12FN3O3S Molecular Weight:309.32 Carbonic anhydrases are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide to form bicarbonate ion plus a proton. Carbonic anhydrases IX (CAIX) and CAXII are hypoxia and HIF-1-inducible proteins located in cellular transmembranes that regulate intra- and extracellular pH under hypoxic conditions and […]