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SB 202190

Jun 20, 2018adminActive small molecule, Products152121-30-7, SB 202190

Cat No:LP000322 Product Name:SB 202190 CAS#152121-30-7 Molecular Formula:C20H14FN3O Molecular Weight:331.34 SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively.1,2 When tested at 10 μM, SB 202190 has negligible effects on a range of other kinases, […]

BMS-5

Jun 20, 2018adminActive small molecule, Products1338247-35-0, BMS-5

Cat No:LP000321 Product Name:BMS-5;LIMKi 3;LIM Kinase Inhibitor I CAS#1338247-35-0 Molecular Formula:C17H14Cl2F2N4OS Molecular Weight:431.29 BMS-5 is a potent inhibitor of activated LIM domain kinases LIMK1 and LIMK2 with IC50 values of 7 and 8 nM, respectively.1 LIMK1 and LIMK2 participate in signal pathways affecting actin dynamics by deactivating cofilin.2,3 This compound can be used to study […]