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2-PMPA

Jun 21, 2018adminActive small molecule, Products173039-10-6, 2-PMPA

Cat No:LP000328 Product Name:2-PMPA CAS#173039-10-6 Molecular Formula:C6H11O7P Molecular Weight:226.12 2-PMPA is a potent and selective inhibitor of GCPII, an enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. 2-PMPA demonstrates robust efficacy in numerous animal models of neurological disease. 2-PMPA is a highly polar compound with multiple negative charges causing significant […]

Monastrol

Cat No:LP000327 Product Name:Monastrol CAS#254753-54-3 Molecular Formula:C14H16N2O3S Molecular Weight:292.35 Monastrol is a cell-permeable small molecule inhibitor of the mitotic kinesin, Eg5. Like other kinesins, Eg5 can drive the movement of microtubules in vitro. In vitro: Previous study found that monastrol did not inhibit progression through S and G2 phases of the cell cycle or centrosome […]