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WZB117

Jun 21, 2018adminActive small molecule, Products1223397-11-2, Glucose Transporter Inhibitor IV, WZB117

Cat No:LP000332 Product Name:WZB117 CAS#1223397-11-2 Molecular Formula:C20H13FO6 Molecular Weight:368.31 WZB117 is an irreversible inhibitor of glucose transporter 1 (Glut1) that blocks glucose transport in diverse cancer cells (IC50 = ~0.6 µM), reducing extracellular lactate and intracellular ATP levels.1 It inhibits cancer cell proliferation (IC50s = 5-10 µM), resulting in cell cycle arrest, senescence, and necrosis […]

HG-9-91-01

Cat No:LP000331 Product Name:HG-9-91-01;SIK inhibitor 1 CAS#1456858-58-4 Molecular Formula:C32H37N7O3 Molecular Weight:567.68 HG-9-91-01 inhibits a number of protein tyrosine kinases that possess a threonine residue at the gatekeeper site, such as Src family members (Src, Lck, and Yes), BTK, and the FGF and Ephrin receptors[1]. HG-9-91-01 demonstrates a strong correlation between the potency of SIK2 inhibition […]