IPI-3063

Cat No:LP000334 Product Name:IPI-3063 CAS#1425043-73-7 IPI-3063 inhibits p110α, p110β, and p110γ with IC50s of 1171±533 nM, 1508±624 nM, and 2187±1529 nM, respectively. IPI-3063 potently reduces mouse B cell proliferation, survival, and plasmablast differentiation while increasing antibody class switching to IgG1. IPI-3063 is a p110δ selective compound with an IC50=0.1 nM in p110δ-specific cell-based assays and cellular […]

Mc-MMAE

Cat No:LP000333 Product Name:Mc-MMAE CAS#863971-24-8 Molecular Formula:C49H78N6O10 Molecular Weight:911.18 Synthesis of maleimidocaproyl-MMAE (mc-MMAE) requires the addition of maleimidocaproic acid to a solution of MMAE in dichloromethane followed by the addition of diethyl cyanophosphonate and diisopropylethylamine.