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BTSA1

Jun 23, 2018adminActive small molecule, Products314761-14-3, BTSA1

Cat No:LP000336 Product Name:BTSA1 CAS#314761-14-3 BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells. BTSA1 has no capacity to directly […]

BAM7

Jun 23, 2018adminActive small molecule, Products331244-89-4, BAM7

Cat No:LP000335 Product Name:BAM7 CAS#331244-89-4 Molecular Formula:C21H19N5O2S Molecular Weight:405.47 BAM7 is selective for the BH3-binding site on BAX. BAM7 activates BAX and BAX-dependent cell death. Whereas treatment with BAX or BAM7 alone has no effect on the liposomes, the combination of BAM7 and BAX yields dose-responsive liposomal release of entrapped fluorophore. BAM7 dose- and time-responsively […]