Cortexolone 17 alpha-propionate

Active small molecule, Products, ,

Cat No:LP000350 Product Name:Cortexolone 17 alpha-propionate;CB-03-01 CAS#19608-29-8 Cortexolone 17 alpha-propionate(CB-03-01) is a new topical and peripherally selective androgen antagonist. IC50 value: Target: Androgen Receptor Cortexolone 17 alpha-propionate (CB-03-01) is a new potent topical antiandrogen potentially useful in acne vulgaris. CB-03-01 1% cream was very well tolerated, and was significantly better than placebo regarding TLC (P […]

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Cobimetinib

Active small molecule, Products,

Cat No:LP000349 Product Name:Cobimetinib CAS#934660-93-2 The EC50 values of Cobimetinib (GDC-0973) for 888MEL and A2058 cells are 0.2 μM, 10 μM, respectivelly. Melanoma cells are treated with EC50 concentration of MEK and PI3K inhibitors for 24 hours (888MEL: 0.05 μM GDC-0973, 2.5 μM GDC-0941; A2058: 2.5 μM GDC-0973, 2.5 μM GDC-0941)[1]. Mitochondrial OXPHOS limits cell […]

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