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Relebactam

Jun 28, 2018adminActive small molecule, Products1174018-99-5, MK-7655, Relebactam

Cat No:LP000358 Product Name:Relebactam;MK-7655 CAS#1174018-99-5 Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes. Target: beta-lactamase Imipenem with Relebactam is active against Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp., including K. pneumoniae carbapenemase (KPC)-producing isolates. The combination of […]

EGF816

Cat No:LP000357 Product Name:EGF816 CAS#1508250-71-2 Molecular Formula:C26H31ClN6O2 Molecular Weight:495.02 EGF816 has inhibitory effect on the mutant cell lines with IC50s of 4, 6, 2 nM in H1975, H3255, and HCC827, respectively, and demonstrates improved ADME and PK properties[1]. EGF816 shows potent inhibition of pEGFR levels in H3255, HCC827, and H1975 cell lines with EC50 values […]