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RVT-501

Cat No:LP000370 Product Name:RVT-501;E6005;lotamilast CAS#947620-48-6 RVT-501 is currently in phase 2 development for patients with mild-to-moderate atopic dermatitis. In mice models, the topical application of RVT-501 produces an immediate antipruritic effect as well as an anti-inflammatory effect with reduced expression of cytokines/adhesion molecules. On the basis of these observed effects, topical RVT-501 ameliorates the appearance […]

BD1063 dhydrochloride

Jul 4, 2018adminActive small molecule, Products206996-13-6, BD1063, BD1063 dhydrochloride

Cat No:LP000369 Product Name:BD1063 dhydrochloride CAS#206996-13-6 BD1063 dose-dependently reduces ethanol self-administration in sP rats (3.3-11 mg/kg) and withdrawn, dependent Wistar rats (4-11 mg/kg) at doses that does not modify mean ethanol self-administration in non-dependent Wistar controls. BD1063 also reduces the breakpoints of sP rats to work for ethanol under a progressive-ratio reinforcement schedule[1]. BD1063 dose-dependently […]