Cat No:LP000390 Product Name:SNS-062 CAS#1270014-40-8 SNS-062 inhibits pBTK in human whole blood with an average IC50 of 50 nM. SNS-062 inhibits WT and C481S BTK with similar IC50s (pBTK IC50s: WT BTK 2.9 nM, C481S BTK 4.4 nM)[1]. In a recombinant kinase assay, IC50s of SNS-062 against WT BTK and C481S BTK are 4.6 nM […]
Cat No:LP000389 Product Name:Emedastine CAS#87233-61-2 Emedastine is a relatively selective, histamine H_ antagonist. In vitro examinations of emedastine’s affinity for histamine receptors demonstrate relative selectivity for the H_ histamine receptor. In vivo studies have shown concentration-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva following topical ocular administration. Emedastine appears to be devoid of effects […]