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DWK-1339

Jul 6, 2018adminActive small molecule, Products1018946-38-7, DWK-1339

Cat No:LP000400 Product Name:DWK-1339;MDR-1339 CAS#1018946-38-7 DWK-1339 (MDR-1339) is an Aβ-aggregation inhibitor, and shows no significant inhibition a panel of CYP isozymes, while it slightly inhibits CYP2C8 (IC50, 31.4 μM). DWK-1339 (3.1-50 μM) dose-dependently blocks the formation of Aβ aggregates, and disaggregates Aβ fibrils. DWK-1339 (1.5-10 μM) also protects cells from this Aβ-induced toxicity[1].

LY2795050

Cat No:LP000399 Product Name:LY2795050 CAS#1346133-08-1 LY2795050 is a novel selective κ-opioid Receptor (KOR) antagonist (IC50=0.72 nM) and has the potential as a PET tracer to image KOR in vivo. IC50 Value: 0.72 nM (κ-opioid Receptor); 25.8 nM (κ-opioid) [1] Target: κ-opioid Receptor in vitro: LY2795050 displays full antagonist activity and high binding affinity and selectivity […]