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SB-742457

Cat No:LP000424 Product Name:SB-742457;GSK-742457; RVT-101; Intepirdine CAS#607742-69-8 SB742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63; exhibits >100-fold selectivity over other receptors. IC50 Value: 9.63 (pKi) Target: 5-HT6 Receptor SB-742457, a 5-HT6 receptor antagonist, which extends into Alzheimer disease (AD) sufferers further highlights the therapeutic promise of this mechanistic approach. Alzheimer’s disease […]

Glesatinib hydrochloride

Jul 17, 2018adminActive small molecule, Products1123838-51-6, Glesatinib, Glesatinib hydrochloride

Cat No:LP000423 Product Name:Glesatinib hydrochloride CAS#1123838-51-6 Glesatinib hydrochloride is an inhibitor of the MET and Axl receptor tyrosine kinase pathways, which drive tumour growth when altered. Target: MET, Axl Glesatinib is an orally bioavailable, small-molecule, multitargeted tyrosine kinase inhibitor with potential antineoplastic activity. MGCD265 binds to and inhibits the phosphorylation of several receptor tyrosine kinases […]