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ML281

Jul 17, 2018adminActive small molecule, Products1404437-62-2, ML281

Cat No:LP000426 Product Name:ML281 CAS#1404437-62-2 ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM. ML281 showed a 550-fold selectivity over AurB and greater than 700-fold selectivity over PKA. target: STK33 IC50: 14 nM [1] ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to […]

Ezutromid

Jul 17, 2018adminActive small molecule, Products945531-77-1, Ezutromid

Cat No:LP000425 Product Name:Ezutromid CAS#945531-77-1 Ezutromid is a novel Small utrophin’s translation modulator with EC50 of 0.4 uM . In vitro: 1) SMT C1100 induces increased levels of utrophin RNA in human muscle cells. 2) Treatment of human DMD cells with SMT C1100 lead to a 2-fold increase in utrophin protein levels at an optimal […]