5-ALA

Active small molecule, Products, , ,

Cat No:LP000428 Product Name:5-Aminolevulinic acid hydrochloride;ALA;5-ALA CAS#5451-09-2 5-Aminolevulinic acid HCl is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles. Target: Others 5-Aminolevulinic acid is a non-fluorescent prodrug that leads to intracellular accumulation of fluorescent porphyrins in malignant gliomas-a finding that is under investigation for intraoperative identification and resection of […]

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EAI045

Active small molecule, Products,

Cat No:LP000427 Product Name:EAI045 CAS#1942114-09-1 EAI045 potently inhibits EGFR Y1173 phosphorylation in H1975 cells (EC50=2 nM), but not in HaCaT cells. EAI045 is an inhibitor of the L858R/T790M mutant with 1000-fold selectivity versus wild type EGFR at 1 mM ATP. Profiling of EAI045 against a panel of 250 protein kinases reveals exquisite selectivity; no other […]

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