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Amenamevir

Jul 19, 2018adminActive small molecule, Products841301-32-4, Amenamevir

Cat No:LP000468 Product Name:Amenamevir CAS#841301-32-4 Amenamevir (ASP2151) inhibits the replication of the HSV strains isolated in Japan and the United States as well as the laboratory-stocked strains. The mean EC50s of Amenamevir against HSV-1 and HSV-2 are 14 (range, 7.7 to 20) and 30 ng/mL (range, 15 to 58), respectively, whereas those of acyclovir (ACV) […]

KNK 437

Jul 19, 2018adminActive small molecule, Products218924-25-5, KNK 437

Cat No:LP000467 Product Name:KNK 437 CAS#218924-25-5 Heat shock protein (Hsp) inhibitor I is a benzylidene lactam compound that prevents the synthesis of inducible Hsps Hsp105, Hsp72, and Hsp40. At 100 μM, it can inhibit the development of thermotolerance in COLO 320 DM cells.1 Its effects on thermotolerance have been studied in the context of clinical […]