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SMER28

Jul 31, 2018adminActive small molecule, Products307538-42-7, SMER28

Cat No:LP000546 Product Name:SMER28 CAS#307538-42-7 SMER28 is an autophagy activator acting via an mTOR-independent mechanism. SMER28 prevents the accumulation of amyloid beta peptide.

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BH3I-1

Jul 30, 2018adminActive small molecule, Products300817-68-9, BH3I-1

Cat No:LP000545 Product Name:BH3I-1 CAS#300817-68-9 BH3I-1 is a Bcl-2 family antagonist, which inhibits the binding of the Bak BH3 peptide to Bcl-xL with a Ki of 2.4±0.2 μM in FP assay. BH3I-1 has a Kd of 5.3 μM against the p53/MDM2 pair.

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