PU-WS13
Cat No:LP000688 Product Name:PU-WS13 CAS#1454619-14-7 Molecular Formula:C17H20Cl2N6S Molecular Weight:411.35 PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM.
SCH 52907
Cat No:LP000687 Product Name:SCH 52907 CAS#922150-11-6 Restores mutant p53 activity. Binds p53 DNA binding domain (Kd = 1-2 μM) and restores wild-type function to many oncogenic mutants by acting as a chaperone. Inhibits ubiquitination of p53 by HDM2. Triggers apoptosis in tumor cell lines and reduces tumor growth in a xenograft model.