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Nintedanib

Sep 5, 2018adminActive small moleculeBIBF-1120, Nintedanib

Name: Nintedanib CAS#: 656247-17-5 (free base) Chemical Formula: C31H33N5O4 Exact Mass: 539.25325 Molecular Weight: 539.62 Elemental Analysis: C, 69.00; H, 6.16; N, 12.98; O, 11.86 Description: Nintedanib, also known as BIBF 1120, is an orally bioavailable inhibitor of vascular endothelial growth factor receptor (VEGFR), fibroblast growth factor receptor (FGFR) and platelet derived growth factor […]

MG132

Sep 5, 2018adminActive small molecule133407-82-6, MG132

Name: MG-132 CAS#: 133407-82-6 Chemical Formula: C26H41N3O5 Exact Mass: 475.30462 Molecular Weight: 475.62 Elemental Analysis: C, 65.66; H, 8.69; N, 8.83; O, 16.82 Description: MG132 is a specific, potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM) . It reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable strains of yeast […]