Gefitinib

Name: Gefitinib CAS#: 184475-35-2 Chemical Formula: C22H24ClFN4O3 Exact Mass: 446.1521 Molecular Weight: 446.9 Elemental Analysis: C, 59.13; H, 5.41; Cl, 7.93; F, 4.25; N, 12.54; O, 10.74 Description: Gefitinib, also known as ZD1839, is an anilinoquinazoline with antineoplastic activity. Gefitinib inhibits the catalytic activity of numerous tyrosine kinases including the epidermal growth factor receptor (EGFR),…

Fingolimod HCl(FTY720)

Name: Fingolimod HCl CAS#: 162359-56-0 (HCl) Chemical Formula: C19H34ClNO2 Exact Mass: Molecular Weight: 343.94 Elemental Analysis: C, 66.35; H, 9.96; Cl, 10.31; N, 4.07; O, 9.30 Description: Fingolimod, also known as FTY720, is an immunosuppressive drug. It is derived from the myriocin (ISP-1) metabolite of the fungus Isaria sinclairii. It is a structural analogue of…

Roxadustat(FG-4592)

Name: Roxadustat CAS#: 808118-40-3 Chemical Formula: C19H16N2O5 Exact Mass: 352.10592 Molecular Weight: 352.35 Elemental Analysis: C, 64.77; H, 4.58; N, 7.95; O, 22.70 Description: Roxadustat, also known as ASP1517 and FG-4592, is an HIF α prolyl hydroxylase inhibitor in a cell-free assay. It stabilizes HIF-2 and induces EPO production and stimulates erythropoiesis. Roxadustat transiently and…

EX-52

  Name: Selisistat CAS#: 49843-98-3 Chemical Formula: C13H13ClN2O Exact Mass: 248.0716 Molecular Weight: 248.71 Elemental Analysis: C, 62.78; H, 5.27; Cl, 14.25; N, 11.26; O, 6.43 Description: Selisistat, also known as EX-527, is a SirT1 inhibitor for treatment of Huntington’s disease. EX-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism. Galectin-9 in Combination With…