Cebranopadol

Active small molecule, Products, ,

Cat No:LP000025 Product Name:Cebranopadol,GRT-6005 CAS:863513-91-1 Purity:99%+ In Stock Cebranopadol binds with high affinity (subnanomolar to nanomolar range) to nociceptin/orphanin FQ peptide (NOP) and opioid receptors, with Ki of 1±0.5 nM, 2.4±1.2 nM, and 64±11 nM for rat NOP, mu-opioid peptide (MOP) receptor, and kappa-opioid peptide (KOP) receptor, and with Ki of 0.9±0.2 nM, 0.7±0.3 nM, […]

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GDC-0084

Active small molecule, Products,

Cat No:LP000024 Product Name:GDC-0084;RG7666 CAS:1382979-44-3 Purity:99%+ In Stock GDC-0084 (Compound 16) maintains inhibition of each of the Class I PI3K isoforms but with more potent inhibition of mTOR. GDC-0084 is also tested in five different GBM cell lines and is found to have antiproliferative EC50s ranging from 0.3 to 1.1 μM[1]. After a 25 mg/kg […]

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