Cat No:LP000027 Product Name:LY2835219,ABEMACICLIB CAS:1231930-82-7 Purity:99%+ In Stock LY2835219 reduces cell viability with the IC50 values ranging from 0.5 μM to 0.7 μM, inhibits Akt and ERK signaling but not mTOR activation at head and neck squamous cell carcinoma (HNSCC) cells[1]. LY2835219 shows inhibition on A375R1-4, M14R, and SH4R with EC50 values ranging from 0.3 […]
Cat No:LP000026 Product Name:(+)-JQ-1,JQ-1 CAS:1268524-70-4 Purity:99%+ In Stock (+)-JQ1 represents a potent, highly specific and Kac competitive inhibitor for the BET family of bromodomains. (+)-JQ1 (100 nM, 48 h) prompts squamous differentiation exhibited by cell spindling, flattening and increased expression of keratin. (+)-JQ1 (250 nM) induces rapid expression of keratin in treated NMC 797 cells […]