Active small molecule – Page 703

A66

Cat No:LP000033 CAS NO:1166227-08-2 Molecular Formula: C17H23N5O2S2 Molecular Weight: 393.53 Purity:98% min Solubility:In DMSO Storage:-20°C A66 is a potent inhibitor of the wild-type and oncogenic forms of p110α but not other class-I PI3K isoforms[1]. The p110α-specific inhibitor A66 (0.7 μM) induces a 75-80% reduction in focus formation by the highly transforming iSH2 mutants KS459delN, DKRMNS560del, […]

Vilanterol trifenatate

Aug 18, 2017adminActive small molecule, Products503070-58-4, Vilanterol trifenatate

Cat No:LP000032 Product Name:Vilanterol trifenatate CAS:503070-58-4 Purity:99%+ In Stock The selectivity of Vilanterol trifenatate for β2-AR over the other β-AR receptor subtypes (β2 and β3) is established by testing the ability of Vilanterol to elicit concentration-dependent increases in cAMP in CHO cells expressing human β1-, β2-, and β3-AR. Vilanterol is demonstrated to be highly selective […]