Active small molecule – Page 410

Ruxolitinib phosphate

Aug 23, 2018adminActive small molecule1092939-17-7, Ruxolitinib phosphate

Cat No:LP000655 Product Name:Ruxolitinib phosphate CAS#1092939-17-7 Ruxolitinib (phosphate) is the first potent JAK1/2 inhibitor with IC50 values of 3.3 nM/2.8 nM, more than 130-fold selectivity for JAK1/2 versus JAK3.

VU0476201

Aug 23, 2018adminActive small molecule1649450-12-3, VU0476201

Cat No:LP000654 Product Name:Ravuconazole CAS#1649450-12-3 ML-352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Ki values of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively.