Active small molecule – Page 409

Monomethyl auristatin E

Aug 23, 2018adminActive small molecule474645-27-7, Monomethyl auristatin E

Cat No:LP000657 Product Name:Monomethyl auristatin E CAS#474645-27-7 Monomethyl auristatin E (MMAE) is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin, and also shows inhibition of antibody-drug conjugates (ADCs) activity.

AZD7545

Aug 23, 2018adminActive small molecule252017-04-2, AZD7545

Cat No:LP000656 Product Name:AZD7545 CAS#252017-04-2 AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.