Active small molecule – Page 247

Bosutinib（SKI-606）

Sep 5, 2018adminActive small molecule380843-75-4, Bosutinib, SKI-606

Name: Bosutinib CAS#: 380843-75-4 Chemical Formula: C26H29Cl2N5O3 Exact Mass: 529.16475 Molecular Weight: 530.44 Elemental Analysis: C, 58.87; H, 5.51; Cl, 13.37; N, 13.20; O, 9.05 Description: Bosutinib, also known as SKI-606, is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Unlike imatinib, bosutinib inhibits […]

Doramapimod（BIRB 796）

Name: Doramapimod CAS#: 285983-48-4 Chemical Formula: C31H37N5O3 Exact Mass: 527.28964 Molecular Weight: 527.66 Elemental Analysis: C, 70.56; H, 7.07; N, 13.27; O, 9.10 Description: Doramapimod, also known as BIRB-796, is a member of the N-pyrazole-N’-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB -796 […]