Cat No:LP000289
Product Name:OSU-03012
CAS No:742112-33-0
Solubility:In DMSO
Storage:-10°C
Description: PDPK1 (PDK1) inhibitor; inhibits Akt signaling
Chemical Name: 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide
Purity: ≥98% (HPLC)
PDPK1 (PDK1) inhibitor; inhibits Akt signaling. Induces apoptosis of PC-3 and medulloblastoma cells, and inhibits growth of a number of tumor cell lines. Sensitizes radiotherapy-induced cell death and enhances cytotoxic effects of chemotherapeutic agents in vitro. Attenuates tumor growth of medulloblastoma xenografts in mice.
