Cat No:LP000148
Product Name:AT-406;SM-406
CAS No:1071992-99-8
Purity: ≥99%
Solubility: In DMSO
Storage: -10°C
AT-406 is an orally bioavailable Smac/DIABLO mimetic and antagonist of the inhibitor of apoptosis proteins (IAPs). It binds to XIAP, cIAP1, and cIAP2 proteins with Ki values of 66.4, 1.9, and 5.1 nM, respectively.1 It has been shown to inhibit cancer cell growth in various human cancer cell lines and to induce apoptosis in xenograft tumors in mice.
