Cat No:LP000287
Product Name:PJ34(hydrochloride)
CAS No:344458-15-7
Purity:≥99%
Solubility:In DMSO
Storage:-10°C
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species.1,2 PJ-34 is an inhibitor of PARPs which can be used in cells or in animals.3,4,5 It binds and inhibits the PARP tankyrase1 (IC50 = 1 μM).6 PJ-34 also inhibits matrix metalloproteinase-2 when used at higher concentrations (IC50 = 56 μM).7
