Cat No:LP000178
Product Name:ZM 323881
CAS No:324077-30-7
Purity: ≥99%
Solubility: In DMSO
Storage: -10°C
ZM-323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro. [1][2]
Reference:[1] J Recept. Signal Transduct. Res. 2003, 23, 239-254.[2] J Clin. Endocrinol. Metab. 2006, 91, 4603-4611.
