Cat No:LP000315
Product Name:NIBR189
CAS#1599432-08-2
Molecular Formula:C21H21BrN2O3
Molecular Weight:429.31
Epstein-Barr virus-induced G protein-coupled receptor 2 (EBI2, also known as GPR183) is an oxysterol receptor involved in B cell migration and function.1 NIBR189 is an antagonist of EBI2 (IC50s = 11 and 15 nM for human and mouse receptors, respectively).2 It is selective for EBI2 over a panel of other receptors, enzymes, and transporters. NIBR189 blocks the oxysterol-induced migration of U937 monocytic cells.2
