Cat No:LP000109
Product Name:Imatinib;CGP57148B;Gleevec;Glivec;STI-571
CAS NO:152459-95-5
Purity: ≥99%
Solubility: In DMSO
Storage: -10°C
Imatinib (mesylate) is a first generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GIST), and other cancers. It selectively targets certain tyrosine kinases, including c-ABL, platelet-derived growth factor receptor, and KIT.1,2 In CML, imatinib (mesylate) inhibits the oncoprotein BCR-ABL, the product of the Philadelphia chromosome gene fusion.
