Cat No:LP000197
Product Name:LY2940680
CAS No:1258861-20-9
Purity: ≥99%
Solubility: In DMSO
Storage: -10°C
Smoothened (Smo) is a GPCR-like receptor that, with Patched, mediates hedgehog (Hh) signaling to regulate gene expression through the Gli transcription factors.1 LY2940680 is an antitumor agent that binds to the human Smo receptor and inhibits Sonic Hh-induced Gli1 expression (IC50 = ~2.4 nM in vitro).2,3,4 The potential anticancer activity of LY2940680 is currently under clinical investigation.
