Ponatinib

Cat No:LP000113 Product Name:AP24534,Ponatinib CAS NO:943319-70-8 Purity: ≥99% Solubility: In DMSO Storage: -10°C Ponatinib (AP24534) potently inhibits native ABL (IC50: 0.37 nM), ABLT315I (IC50: 2.0 nM), and other clinically important ABL kinase domain mutants (IC50: 0.30-0.44 nM). Ponatinib also inhibits SRC (IC50: 5.4 nM) and members of the VEGFR, FGFR, and PDGFR families of receptor…